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  • Chemical Biology

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    Item specifics

    New with box: A brand-new, unused, unworn and undamaged item in its original packaging (such as the original box ... Read moreabout the condition
    Brand: ASICS
    Sports: Running Gender: Womens
    Material: Synthetic Main Colour: Pink
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    Colour: Pink Style: Running Shoes
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    Aventik IM12 Nano 9FT LW3, 4, 5, 6 Fast Action Light Weight Freshwater Fly Rods

    Here’s some medicinal chemistry combined with synthetic biology for you. Many people are used to thinking in terms of finding small-molecule probes for various cell targets, and those are valuable things. But what if you want to control a certain population of (for example) ion channels, but there aren’t any compounds that will do the… Aventik Super Light Mesh Fabric Fly Fishing Vest,Fishing Mesh Vest Wading NEW
  • Chemical News

    Avento Fitness Yoga Mat Exercise Fitness Gym Pilates 173x61 cm PVC 41VH-GRB-Uni

    BAYER LEVERKUSEN MATCH PREPERED SHIRT TRIKOT BUNDESLIGA ROLFES I was interested to see this paper, which goes into detail on a chemical phenomenon that many have seen but no one understands very well: triboluminescence. That word meets with a blank stare or instant recognition; there’s not much in between. It means “emission of light when a material is physically broken”, and that encompasses… Avento Yoga Mat Microfiber Suede with Print orange Exercise Equipment Carpet
  • Analytical Chemistry

  • Cancer

    Making and Measuring Multivalency

    Here’s an unusual paper that’s studying receptor behavior on cell surfaces by use of atomic force microscopy. (Here’s the SI file, which is free to access). The authors took the marketed VEGF inhibitor vandetanib (VD6474) and attached it through linkers to the AFM tip, and then scanned around the surface of live human umbilical v… Avet HX5 2 Gunmetal Raptor Lever Drag 2-Speed Reel
  • Drug Assays

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    BB026 MOTHERBOARD & 2 X GYRO BOARDS 6.5 SELF BALANCE HOVER BOARD 350w Lithium A common question – well, it should be a common question, anyway – is “How do I make sure that this compound collection is a useful one to screen?” There are alternative forms that come down to the same issues – if you’re putting together a new focused screening set, what should be in it?… Read More
  • Biological News

  • Business and Markets

  • Analytical Chemistry

    A Close Look at Fragments

    Here’s a look from the D. E. Shaw research team at fragment binding, and even if you don’t do fragment-based drug discovery, it’s worth a read. That’s because the mechanisms by which fragments bind to proteins are most likely the fundamental ones by which larger molecules bind as well; this is the reductionist look at… Read More
  • Analytical Chemistry

    A Look at Proteins in Living Cells

    We spend a lot of time in this sort of work thinking about protein structures. Traditionally that’s been the province of X-ray crystallography, later joined by solution NMR, and more latterly by cryo-electron microscopy. Each of these has its own set of advantages and disadvantages, but one big split is between the solid phase (X-ray… Avid Carp 3+ Rod Holdall
  • Academia (vs. Industry)

    Startup Culture, Starting

    BBB Icarus Cycling Helmet + snap on helmet cover Many readers of this blog work in the biopharma industry, naturally, and of those, many are in and around the (few) locations where a great many of the companies in the industry are born. I myself am in the Boston/Cambridge area, famously thick with companies large and small, and then you have the Bay area… Avid Carp A-Spec Compact Cooler A0430026 NEW
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